Recent Publications

Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes.
Ullrich S, Leidescher S, Feodorova Y, Thanisch K, Fini JB, Kaspers B, Weber F, Markova B, Führer D, Romitti M, Krebs S, Blum H, Leonhardt H, Costagliola S, Heuer H, Solovei I. https://doi: 10.3389/fcell.2025.1571466

Expansion of Interleukin-22-Producing Type 3 Innate Lymphoid Cells in the Gut of Tristetraprolin-Deficient Mice.
de de Toeuf B, Melchior M, La C, Villanueva Alcantara A, Azouz A, Martens V, La C, Dubois I, Vande Velde S, Meyer L, Nguyen M, Thomas S, Libert F, Dumoutier L, Blackshear PJ, Goriely S. https://doi.org/10.1002/eji.202350892

Extra-embryonic mesoderm during development and in in vitro models.
Eliana Nehme, Amitesh Panda, Isabelle Migeotte, Vincent Pasque https://doi.org/10.1242/dev.204624

HMGA2 Overexpression in Papillary Thyroid Cancer Promotes Thyroid Cell Dedifferentiation and Invasion, and These Effects Are Counteracted by Suramin.
Van Branteghem C, Henry N, Craciun L, Maenhaut C. https://doi.org/10.3390/ijms26041643


An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration
Maryam Marefati, Valeria Fernandez-Vallone, Morgane Leprovots, Gabriella Vasile, Frédérick Libert, Anne Lefort, Gilles Dinsart, Achim Weber, Jasna Jetzer, Marie-Isabelle Garcia, Gilbert Vassart. https://doi.org/10.1242/dev.204654

The History of Chromosomal Instability in Genome-Doubled Tumors
Toby M Baker, Siqi Lai, Andrew R Lynch, Tom Lesluyes, Haixi Yan, Huw A Ogilvie, Annelien Verfaillie, Stefan Dentro, Amy L Bowes, Nischalan Pillay, Adrienne M Flanagan, Charles Swanton, Paul T Spellman, Maxime Tarabichi, Peter Van Loo. Cancer discovery 2024/10/4

Human carbamylome description identifies carbamylated alpha2-macroglobulin and hemopexin as two novel autoantigens in early rheumatoid arthritis.
Sidiras P., Lechanteur J., Imbault V., Sokolova T., Durez P., Gangji V., Communi D., and Rasschaert J. Human(2022) Rheumatology 61(7), 2826-2834 https://pubmed.ncbi.nlm.nih.gov/34788409/

Profiling the complex rearrangement architecture of sarcoma
S Waise, T Lesluyes, J Demeulemeester, M Tarabichi, AM Flanagan, N Pillay, P Van Loo. Journal of Pathology 2024/8/1

Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Adriana Salcedo, Maxime Tarabichi, Alex Buchanan, Shadrielle MG Espiritu, Hongjiu Zhang, Kaiyi Zhu, Tai-Hsien Ou Yang, Ignaty Leshchiner, Dimitris Anastassiou, Yuanfang Guan, Gun Ho Jang, Mohammed FE Mootor, Kerstin Haase, Amit G Deshwar, William Zou, Imaad Umar, Stefan Dentro, Jeff A Wintersinger, Kami Chiotti, Jonas Demeulemeester, Clemency Jolly, Lesia Sycza, Minjeong Ko, David C Wedge, Quaid D Morris, Kyle Ellrott, Peter Van Loo, Paul C Boutros. Nature Biotechnology 2024/6/11 https://www.nature.com/articles/s41587-024-02250-y

Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of pleural mesotheliomas to CDK4/6 inhibition
Sabine Paternot, Eric Raspé, Clément Meiller, Maxime Tarabichi, Jean‐Baptiste Assié, Frederick Libert, Myriam Remmelink, Xavier Bisteau, Patrick Pauwels, Yuna Blum, Nolwenn Le Stang, Séverine Tabone‐Eglinger, Françoise Galateau‐Sallé, Christophe Blanquart, Jan P Van Meerbeeck, Thierry Berghmans, Didier Jean, Pierre P Roger. Molecular Oncology 2024/4 https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13351

The cerebrospinal fluid proteomic response to traumatic and non-traumatic acute brain injury: a prospective study.
Santacruz C.H., Vincent J.L., Duitama J., Bautista E., Imbault V., Bruneau M., Creteur J., Brimioulle S., Communi D.*, and Taccone F.S.* (*equal contribution)(2022) Neurocrit. Care 37(2), 463-470 https://pubmed.ncbi.nlm.nih.gov/35523916/

Genomic evolution shapes prostate cancer disease type
Dan J Woodcock, Atef Sahli, Ruxandra Teslo, Vinayak Bhandari, Andreas J Gruber, Aleksandra Ziubroniewicz, Gunes Gundem, Yaobo Xu, Adam Butler, Ezequiel Anokian, Bernard J Pope, Chol-Hee Jung, Maxime Tarabichi, Stefan C Dentro, J Henry R Farmery, Peter Van Loo, Anne Y Warren, Vincent Gnanapragasam, Freddie C Hamdy, G Steven Bova, Christopher S Foster, David E Neal, Yong-Jie Lu, Zsofia Kote-Jarai, Michael Fraser, Robert G Bristow, Paul C Boutros, Anthony J Costello, Niall M Corcoran, Christopher M Hovens, Charlie E Massie, Andy G Lynch, Daniel S Brewer, Rosalind A Eeles, Colin S Cooper, David C Wedge. Cell Genomics 2024/3/13 https://www.cell.com/cell-genomics/fulltext/S2666-979X(24)00038-7

Aneuploidy and complex genomic rearrangements in cancer evolution
Toby M Baker, Sara Waise, Maxime Tarabichi, Peter Van Loo. Nature cancer 2024/2. https://www.nature.com/articles/s43018-023-00711-y

Pan-cancer subclonal mutation analysis of 7,827 tumors predicts clinical outcome
Yujie Jiang, Matthew D Montierth, Kaixian Yu, Shuangxi Ji, Shuai Guo, Quang Tran, Xiaoqian Liu, Seung Jun Shin, Shaolong Cao, Ruonan Li, Yuxin Tang, Tom Lesluyes, Scott Kopetz, Jaffer Ajani, Pavlos Msaouel, Sumit K Subudhi, Ana Aparicio, Padmanee Sharma, John Paul Shen, Anil K Sood, Maxime Tarabichi, Jennifer R Wang, Marek Kimmel, Peter Van Loo, Hongtu Zhu, Wenyi Wang. bioRxiv 2024.07. 03.601939 https://www.biorxiv.org/content/10.1101/2024.07.03.601939v1.abstract

Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells
Adrien Tourneur, Joel Rodrigues Vitoria, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frederick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours. bioRxiv 2024.02. 15.580495 https://www.biorxiv.org/content/10.1101/2024.02.15.580495v2.abstract

Sentons-nous le goût des aliments uniquement avec notre langue ?
The Conversation Benjamin Beck and Alizée Vercauteren Drubbel (April 2024) – (124.000 vues) https://theconversation.com/sentons-nous-le-gout-des-aliments-uniquement-avec-notre-langue-224548

Cerebral apolipoprotein E and amyloid precursor-like protein 1 as risk factors for chronic neurodegeneration after non-traumatic acute brain injury (ABI).
Santacruz C.H., Vincent J.L., Imbault V., Bruneau M., Creteur J., Brimioulle S., Raussens V., Communi D.*, and Taccone F.S.* (*equal contribution) (2023) Crit. Care 27(1):249. doi: 10.1186/s13054-023-04538-y

Understanding the dosage-dependent role of Dicer1 in thyroid tumorigenesis
Rojo-Pardillo M.; Godefroid, L.; Dom, G.; Lefort, A.; Libert, F.; Robaye, B.; Maenhaut, C. International Journal of Molecular Sciences 2024, 25, 10701. https://doi.org/10.3390/ijms251910701

Live Imaging and Characterization of Microglia Dynamics in the Zebrafish Embryo
Montanari A, Wittamer V. J Vis Exp. 2024 May 17;(207). doi: 10.3791/66533. https://app.jove.com/t/66533/live-imaging-characterization-microglia-dynamics-zebrafish