Recent Publications
Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells
Adrien Tourneur, Joel Rodrigues Vitoria, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frederick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours. bioRxiv 2024.02. 15.580495 https://www.biorxiv.org/content/10.1101/2024.02.15.580495v2.abstract
Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit absorptive and barrier alterations
Alia Hadefi, Morgane Leprovots, Gilles Dinsart, Maryam Marefati, Marjorie Vermeersch, Daniel Monteyne, David Pérez-Morga, Anne Lefort, Frédérick Libert, Laurine Verset, Claire Liefferinckx, Christophe Moreno, Jacques Devière, Eric Trépo, Marie-Isabelle Garcia, Gastro Hep Advances, 2024, 100599, ISSN 2772-5723, https://doi.org/10.1016/j.gastha.2024.100599.
Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
H. Lasolle, A. Schiavo, A. Tourneur, P. Gillotay, B. de F. da Fonseca, L. Ceolin, O. Monestier, B. Aganahi, L. Chomette, M. M. L. Kizys, L. Haenebalcke, T. Pieters, S. Goossens, J. Haigh, V. Detours, A. L. S. Maia, S. Costagliola, and M. Romitti, Oncogene 1–16 (2023) doi:10.1038/s41388-023-02889-y.
Thyroid-on-a-chip: An Organoid Platform For In Vitro Assessment of Endocrine Disruption
Carvalho, D. J., Kip, A. M., Romitti, M., Nazzari, M., Tegel, A., Stich, M., Krause, C., Caiment, F., Costagliola, S., Moroni, L., Giselbrecht, S., Adv. Healthcare Mater. 2022, 2201555. https://doi.org/10.1002/adhm.202201555
Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
Mírian Romitti, Barbara de Faria da Fonseca, Gilles Doumont, Pierre Gillotay, Adrien Tourneur, Sema Elif Eski, Gaetan Van Simaeys, Laura Chomette, Helene Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, Samuel Refetoff, Sabine Costagliola Nat Commun 13, 7057 (2022). https://doi.org/10.1038/s41467-022-34776-7, https://doi.org/10.1038/s41467-022-34776-7
Foxe1 orchestrates thyroid and lung cell lineage divergence in mouse stem cell-derived organoids
Fonseca B F, Barbee C, Romitti M, Eski S E, Gillotay P, Monteyne D, Perez-Morga D, Refetoff S, Singh S P and Costagliola S 2022 bioRxiv 2022.05.16.492074. https://doi.org/doi:10.1101/2022.05.16.492074.
Cold Atmospheric Plasma Differentially Affects Cell Renewal and Differentiation of Stem Cells and Apc-Deficient-Derived Tumor Cells in Intestinal Organoids.
A. Hadefi, M. Leprovots, M. Thulliez, O. Bastin, A. Lefort, F. Libert, A. Nonclercq, A. Delchambre, F. Reniers, J. Deviere, MI Garcia. Cell Death Discovery (2022) 8:66 ; https://doi.org/10.1038/s41420-022-00835-7.
Single-cell trajectory inference guided enhancement of thyroid maturation in vitro using TGF-beta inhibition
M. Romitti, S. E. Eski, B. F. Fonseca, P. Gillotay, S. P. Singh, and S. Costagliola, Front Endocrinol12, 657195 (2021).