Open Positions


6th PhD Day will take place on December 13, 2020
Holleken Farm

IRIBHM international PhD Programme
The 2019 Call is closed !

   Recent Publications

"Phosphoinositide 5-phosphatases SKIP and SHIP2 in ruffles, the endoplasmic reticulum and the nucleus: an update". Ana Raquel Ramos, Somadri Ghosh, Tara Suhel, Clément Chevalier, Eric Owusu Obeng, Bohumil Fafílek, Pavel Krejci, Benjamin Beck, Christophe Erneux (2019) Adv Biol Regulation. in press.

"Macrophage-expressed gene (mpeg)1 identifies a subpopulation of B cells in the adult zebrafish",Giuliano Ferrero, Etienne Gomez, Sowmya lyer, Mireia Rovira, Magali Miserocchi, David M. Langenau, Julien Y. Bertrand and Valérie Wittamer. (2019) Journal of Leukocyte Biology. In press

"Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis", Ingrid Dubois-Vedrenne, Olivier De Henau, Virginie Robert, Francina Langa, Diana Al Delbany, Olivier Vosters, Edgar Angelats-Canals, Maxime Vernimmen, Souphalone Luangsay, Valérie Wittamer, and Marc Parmentier, (2019) Frontiers in Oncology, In press

"Inhibition of the thyroid hormonogenic H2O2 production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound", Nicoletta Giusti, Pierre Gillotay, Achim Trubiroha, Robert Opitz, Jacques-Emile Dumont, Sabine Costagliola, Xavier De Deken, Molecular and Cellular Endocrinology, 2019, 110635, ISSN 0303-7207,

“Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development”. Benoit Haerlingen, Robert Opitz, Isabelle Vandernoot, Achim Trubiroha, Pierre Gillotay, Nicoletta Giusti, Sabine Costagliola. 2019, Sept 11, Thyroid;

"Lgr5 controls extracellular matrix production by stem cells in the developing intestine."Fernandez-Vallone V., Leprovots M., Gerbier R., Ribatallada-Soriano D., Lefort A., Libert F., Vassart G., Garcia MI. BIORXIV/2019/757641.

“Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways,” Bonnefont, L. Tiberi, J. van den Ameele, D. Potier, Z. B. Gaber, X. Lin, A. Bilheu, A. Herpoel, F. D. Velez Bravo, F. Guillemot, S. Aerts, and P. Vanderhaeghen, Neuron, Jul. 2019.

“Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo”. B. Saykali, N. Mathiah, W. Nahaboo, M.-L. Racu, L. Hammou, M. Defrance, and I. Migeotte, eLife, vol. 8, p. e42434, 2019.

"Lipid phosphatases SKIP and SHIP2 regulate fibronectin-dependent cell migration in glioblastoma". Ramos AR, Ghosh S, Dedobbeleer M, Robe PA, Rogister B, Erneux C.FEBS J. 2019 Jan 29. doi: 10.1111/febs.14769.

"The impact of PI 5-phosphatases on phosphoinositides in cell function and human disease" Ana Raquel Ramos, Somadri Ghosh, Christophe Erneux (2019)  J. Lipid Res. 60:  2.  276-286 Feb. 


Biomedical Research Seminars
Campus Erasme - 1PM

October 31 (Auditoire Louise Popelin)

November 21 (Auditoire Louise Popelin)
Thomas Marichal
I3-Immunophysiology, Département des sciences fonctionnelles (DSF) GIGA & Faculty of Veterinary Medicine, University of Liege
“Environment and allergic asthma: myeloid cells on stage”
Host: Valerie Wittamer

November 28 (Auditoire Louise Popelin)
Stanislas Goriely
Institute for Medical Immunology (IMI)
Faculté de Médecine, Campus de Charleroi, Gosselies (Biopark) ULB
“Molecular Regulation of Cytokines in Inflammation”
Host: Valerie Wittamer

December 5 (Auditoire Louise Popelin)
Vladyslav Vyazovskiy
Department of Physiology, Anatomy and Genetics, Sleep and Circadian Neuroscience Institute (SCNi)
University of Oxford
"Why do we sleep? From sleep regulation to function"
Host: Alban de Kerhchove

December 12 (Auditoire Louise Popelin)
Sumeet Pal Singh
"From individual to community: a single-cell approach to understanding how individual cells generate functional organs"
Host: S. Costagliola

   Press release

New European H2020 research project
The influence of endocrine disruptors on the male and female thyroid gland

The new European collaborative project SCREENED aims to develop three-dimensional (3D) cell-based in vitro tests to better characterize the effects of endocrine disruptors on thyroid functions. This method will overcome the limitations of existing tests, being more sensitive, at low doses of exposure to chemicals, and enabling the prediction of their toxicity on human health in a sex-specific manner. Sabine Costagliola Lab at IRIBHM is the Belgian partner of this ambitious and innovative project.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 825745.

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