Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction

Adriana Salcedo, Maxime Tarabichi, Alex Buchanan, Shadrielle MG Espiritu, Hongjiu Zhang, Kaiyi Zhu, Tai-Hsien Ou Yang, Ignaty Leshchiner, Dimitris Anastassiou, Yuanfang Guan, Gun Ho Jang, Mohammed FE Mootor, Kerstin Haase, Amit G Deshwar, William Zou, Imaad Umar, Stefan Dentro, Jeff A Wintersinger, Kami Chiotti, Jonas Demeulemeester, Clemency Jolly, Lesia Sycza, Minjeong Ko, David C Wedge, Quaid D Morris, Kyle Ellrott, Peter Van Loo, Paul C Boutros. Nature Biotechnology 2024/6/11 https://www.nature.com/articles/s41587-024-02250-y

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Profiling the complex rearrangement architecture of sarcoma

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Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of pleural mesotheliomas to CDK4/6 inhibition