Recent Publications

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment-Integrated Organ-On-Chip Models. Adv. Ther
Moresi, F., Noto, F., Vasudevan, J., Bisteau, X., Adriani, G., and Pavesi, A. (2025)

Development of An Analytical Model for Assessing the Adsorptive Properties of Traditional Medicinal Formulations from Burkina Faso in Relation to Snake Venom Proteins
Moumouni BANDE, Cédric DELPORTE, Abdoul Karim SAKIRA, Axelle BOUREZ, Virginie IMBAULT, Xavier BISTEAU, Charles SOMBIE, Touridomon Issa SOME, Pierre VAN. ANTWERPEN.

Dysregulation of Inositol Polyphosphate 5-Phosphatase OCRL in Alzheimer's Disease: Implications for Autophagy Dysfunction
Kunie Ando, May Thazin Htut, Eugenia Maria Antonelli, Andreea-Claudia Kosa, Lidia Lopez-Gutierrez, Carolina Quintanilla-Sánchez, Emmanuel Aydin, Emilie Doeraene, Siranjeevi Nagaraj, Ana Raquel Ramos, Katia Coulonval, Pierre P Roger, Jean-Pierre Brion, Karelle Leroy.

Development of 3D organoid models to study aggressive thyroid cancers
Eduardo Rios-Morris, Verla Tientcheu Ngaffi, Sabine Costagliola, Mírian Romitti.

Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish
Sema Elif Eski, Jiarui Mi, Macarena Pozo-Morales, Gabriel Garnik Hovhannisyan, Camille Perazzolo, Rita Manco, Imane Ez-Zammoury, Dev Barbhaya, Anne Lefort, Frédérick Libert, Federico Marini, Esteban N Gurzov, Olov Andersson, Sumeet Pal Singh.

Lactate and gastrointestinal complications during enteral nutrition in pediatric ECMO patients: a retrospective cohort study
Bruna Pinheiro Machado, Yadigar Ziylan, Alexia Detheux, Ariane Willems, Viviane De Maertelaer, Corinne De Laet, Shancy Rooze.

Systematic analysis of A-to-I RNA editing upon release of ADAR from the nucleolus
Ruben Lattuca, Rümeyza Bascetin, Vincent Detours, Denis L J Lafontaine.

Functional Thyroid Organoids—Powerful Stem Cell-Derived Models in Basic and Translational Research
Meghna Parakkal Shankar, Alessandra Boggian, Daniela Aparicio-Quiñonez, Sami Djerbib, Eduardo Rios-Morris, Sabine Costagliola, Mírian Romitti.

Zebrafish in neurodevelopmental disorders studies: Genetic models and pathological involvement of microglia.
Fatemeh Hassani Nia, Valerie Wittamer.

Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes.
Ullrich S, Leidescher S, Feodorova Y, Thanisch K, Fini JB, Kaspers B, Weber F, Markova B, Führer D, Romitti M, Krebs S, Blum H, Leonhardt H, Costagliola S, Heuer H, Solovei I.

Expansion of Interleukin-22-Producing Type 3 Innate Lymphoid Cells in the Gut of Tristetraprolin-Deficient Mice.
de de Toeuf B, Melchior M, La C, Villanueva Alcantara A, Azouz A, Martens V, La C, Dubois I, Vande Velde S, Meyer L, Nguyen M, Thomas S, Libert F, Dumoutier L, Blackshear PJ, Goriely S.

Extra-embryonic mesoderm during development and in in vitro models.
Eliana Nehme, Amitesh Panda, Isabelle Migeotte, Vincent Pasque

HMGA2 Overexpression in Papillary Thyroid Cancer Promotes Thyroid Cell Dedifferentiation and Invasion, and These Effects Are Counteracted by Suramin.
Van Branteghem C, Henry N, Craciun L, Maenhaut C.


An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration
Maryam Marefati, Valeria Fernandez-Vallone, Morgane Leprovots, Gabriella Vasile, Frédérick Libert, Anne Lefort, Gilles Dinsart, Achim Weber, Jasna Jetzer, Marie-Isabelle Garcia, Gilbert Vassart.

The History of Chromosomal Instability in Genome-Doubled Tumors
Toby M Baker, Siqi Lai, Andrew R Lynch, Tom Lesluyes, Haixi Yan, Huw A Ogilvie, Annelien Verfaillie, Stefan Dentro, Amy L Bowes, Nischalan Pillay, Adrienne M Flanagan, Charles Swanton, Paul T Spellman, Maxime Tarabichi, Peter Van Loo. Cancer discovery

Human carbamylome description identifies carbamylated alpha2-macroglobulin and hemopexin as two novel autoantigens in early rheumatoid arthritis.
Sidiras P., Lechanteur J., Imbault V., Sokolova T., Durez P., Gangji V., Communi D., and Rasschaert J. Human(2022) Rheumatology 61(7), 2826-2834

Profiling the complex rearrangement architecture of sarcoma
S Waise, T Lesluyes, J Demeulemeester, M Tarabichi, AM Flanagan, N Pillay, P Van Loo. Journal of Pathology 2024/8/1

Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Adriana Salcedo, Maxime Tarabichi, Alex Buchanan, Shadrielle MG Espiritu, Hongjiu Zhang, Kaiyi Zhu, Tai-Hsien Ou Yang, Ignaty Leshchiner, Dimitris Anastassiou, Yuanfang Guan, Gun Ho Jang, Mohammed FE Mootor, Kerstin Haase, Amit G Deshwar, William Zou, Imaad Umar, Stefan Dentro, Jeff A Wintersinger, Kami Chiotti, Jonas Demeulemeester, Clemency Jolly, Lesia Sycza, Minjeong Ko, David C Wedge, Quaid D Morris, Kyle Ellrott, Peter Van Loo, Paul C Boutros. Nature Biotechnology 2024/6/11

Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of pleural mesotheliomas to CDK4/6 inhibition
Sabine Paternot, Eric Raspé, Clément Meiller, Maxime Tarabichi, Jean‐Baptiste Assié, Frederick Libert, Myriam Remmelink, Xavier Bisteau, Patrick Pauwels, Yuna Blum, Nolwenn Le Stang, Séverine Tabone‐Eglinger, Françoise Galateau‐Sallé, Christophe Blanquart, Jan P Van Meerbeeck, Thierry Berghmans, Didier Jean, Pierre P Roger.