Recent Publications
Central role of PD-L1 in cardioprotection resulting from P2Y4 nucleotide receptor loss
Michael Horckmans, Esteban Diaz Villamil, Mariaelvy Bianchini, Lucas De Roeck and Didier Communi. Frontiers in Immunology (2022). https://doi.org/10.3389/fimmu.2022.1006934
UTP regulates the cardioprotective action of transplanted stem cells derived from mouse cardiac adipose tissue
Esteban Diaz Villamil, Lucas De Roeck, Marion Vanorlé and Didier Communi. Frontiers in Pharmacology (2022) https://doi.org/10.3389/fphar.2022.906173
Regionally specific levels and patterns of keratin 8 expression in the mouse embryo visceral endoderm emerge upon anterior-posterior axis determination
Evangéline Despin-Guitard, Ronan Quenec’Hdu, Wallis Nahaboo, Nicole Schwarz, Rudolf E.Leube, Claire Chazaud and Isabelle Migeotte. Frontiers in Cell and Developmental Biology (2022) https://doi.org/10.3389/fcell.2022.1037041
Cerebrospinal Fluid Proteomics in Friedreich Ataxia Reveals Markers of Neurodegeneration and Neuroinflammation.
Frontiers in Neuroscience, 16, 885313. https://doi:10.3389/ fnins.2022.885313. Imbault, V., Dionisi, C., Naeije, G., Communi, D., & Pandolfo, M. (2022).
Danger-associated Molecular Patterns After Traumatic and Nontraumatic Acute Brain Injury: A Prospective Study.
Journal of neurosurgical anesthesiology. https://doi:10.1097/ANA.0000000000000916. Santacruz, C. A., Vincent, J. L., Duitama, J., Bautista, E., Imbault, V., Bruneau, M., Creteur, J., Brimioulle, S., Communi, D., & Taccone, F. (2023). vCSF
Proprioceptors-enriched neuronal cultures from induced pluripotent stem cells from Friedreich ataxia patients show altered transcriptomic and proteomic profiles, abnormal neurite extension.
Brain Communications, 5(1), fcad007. https://doi:10.1093/braincomms/fcad007. Dionisi, C., Chazalon, M., Rai, M., Keime, C., Imbault, V., Communi, D., Puccio, H., Schiffmann, S. N., & Pandolfo, M. (2023).
Association of cerebrospinal fluid protein biomarkers with outcomes in patients with traumatic and non-traumatic acute brain injury: systematic review of the literature.
Critical care, 25(1), 278. https://doi:10.1186/s13054-021-03698-z. Santacruz, C. A., Vincent, J. L., Bader, A., Rincón-Gutiérrez, L. L., Dominguez-Curell, C., Communi, D., & Taccone, F. (2021).
Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
Mírian Romitti, Barbara de Faria da Fonseca, Gilles Doumont, Pierre Gillotay, Adrien Tourneur, Sema Elif Eski, Gaetan Van Simaeys, Laura Chomette, Helene Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, Samuel Refetoff, Sabine Costagliola Nat Commun 13, 7057 (2022). https://doi.org/10.1038/s41467-022-34776-7, https://doi.org/10.1038/s41467-022-34776-7
Loss of tetraspanin-7 expression reduces pancreatic beta-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism
Kerry McLaughlin, Samuel Acreman, Sameena Nawaz, Joseph Cutteridge, Anne Clark, Jakob G. Knudsen, Geoffrey Denwood, Aliya F. Spigelman, Jocelyn E. Manning Fox, Sumeet Pal Singh, Patrick E. MacDonald, Benoit Hastoy, Quan Zhang, Diabetic Medicine, 20 October 2022, https://doi.org/10.1111/dme.14984
Murine Thyroid IL-4 Expression Worsens Hypothyroidism on Iodine Restriction and Mitigates Graves Disease Development
Merakchi K, Djerbib S, Soleimani M, Dumont JE, Miot F, De Deken X. Endocrinology. 2022 Sep 1;163(9):bqac107. doi: 10.1210/endocr/bqac107.PMID: 35881515
Cellular senescence modulates progenitor cell expansion during axolotl limb regeneration
Qinghao Yu, Hannah E. Walters, Giovanni Pasquini, Sumeet Pal Singh, Daniel León-Periñán, Andreas Petzold, Preethi Kesavan, Cristina Subiran, Ines Garteizgogeascoa, Dunja Knapp, Anne Wagner, Andrea Bernardos, María Alfonso, Gayathri Nadar, Andreas Dahl, Volker Busskamp, Ramón Martínez-Máñez, Maximina H. Yun. bioRxiv, 2022.09.01.506196; https://doi.org/10.1101/2022.09.01.506196
In vivo imaging of calcium dynamics in zebrafish hepatocytes
Pozo-Morales, M., Garteizgogeascoa, I., Perazzolo, C., So, J., Shin, D. and Singh, S.P. (2022), . Hepatology. Accepted Author Manuscript. https://doi.org/10.1002/hep.32663
Zebrafish Galectin 3 binding protein (Lgals3bp) is the target antigen of the microglial 4C4 monoclonal antibody
Mireia Rovira, Alice Montanari, Latifa Hammou, Laura Chomette, Magali Miserocchi, Jennifer Pozo, Virginie Imbault, Xavier Bisteau, Valérie Wittamer https://doi.org/10.1101/2022.04.05.486973
Foxe1 orchestrates thyroid and lung cell lineage divergence in mouse stem cell-derived organoids
Fonseca B F, Barbee C, Romitti M, Eski S E, Gillotay P, Monteyne D, Perez-Morga D, Refetoff S, Singh S P and Costagliola S 2022 bioRxiv 2022.05.16.492074. https://doi.org/doi:10.1101/2022.05.16.492074.
An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4
Audrey G. Reeves, Angel Gonzalez-Valero, Patrick J. Moon, Edward Miller, Katia Coulonval, Steven W. M. Crossley, Xiao Xie, Dan He, Patricia Z. Musacchio, Alec H. Christian, Jeffrey M. McKenna, Richard A. Lewis, Eric Fang, Dustin Dovala, Yipin Lu, Lynn M. McGregor, Markus Schirle, John A. Tallarico, Pierre P. Roger, F. Dean Toste, and Christopher J. Chang. ChemRxiv (April 2022) https//doi.org/10.26434/chemrxiv-2022-9p94z
Monoclonal antibodies to activated CDK4: Use to investigate normal and cancerous cell cycle regulation and involvement of phosphorylations of p21 and p27
Coulonval, K., Vercruysse, V., Paternot, S., Pita, J.M., Corman, R., Raspé, E., Roger, P.P. Cell Cycle, 21(1) :12-32 (jan. 2022)
Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of malignant pleural mesotheliomas to CDK4/6 inhibition
Paternot S, Raspé E, Meiller C, Tarabichi M, Assié JB, Libert F, Remmelink M, Bisteau X, Pauwels P, Blum Y, Le Stang N, Tabone-Eglinger S, Galateau-Salle F, Blanquart C, Van Meerbeeck JP, Berghmans T, Jean D, Roger PP. bioRxiv (april 2022) doi: https://doi.org/10.1101/2022.04.11.487857
The Atypical Chemerin Receptor GPR1 Displays Different Modes of Interaction with β-arrestins in Humans and Mice with Important Consequences on Subcellular Localization and Trafficking
Degroot, G-N, Lepage, V., Parmentier M. and Springael, J-Y (2022) Cells in press.
Signal Transduction by VIP and PACAP Receptors
I. Langer, J. Jeandriens, A. Couvineau, S. Sanmukh, D. Latek. Biomedicines (2022) 9;10(2):406. doi: 10.3390/biomedicines10020406.
Cold Atmospheric Plasma Differentially Affects Cell Renewal and Differentiation of Stem Cells and Apc-Deficient-Derived Tumor Cells in Intestinal Organoids.
A. Hadefi, M. Leprovots, M. Thulliez, O. Bastin, A. Lefort, F. Libert, A. Nonclercq, A. Delchambre, F. Reniers, J. Deviere, MI Garcia. Cell Death Discovery (2022) 8:66 ; https://doi.org/10.1038/s41420-022-00835-7.