Recent Publications
Keratin filaments mediate the expansion of extra-embryonic membranes in the post-gastrulation mouse embryo
Wallis Nahaboo, Sema Elif Eski, Evangéline Despin-Guitard, Marjorie Vermeersch, Marie Versaevel, Bechara Saykali, Daniel Monteyne, Sylvain Gabriele, Thomas M Magin, Nicole Schwarz, Rudolf E Leube, An Zwijsen, David Perez-Morga, Sumeet Pal Singh, Isabelle Migeotte. The EMBO Journal (2022) e108747.https://doi.org/10.15252/embj.2021108747
Nrf2 promotes thyroid development and hormone synthesis
Pierre Gillotay, Mirian Romitti, Benjamin Dassy, Benoit Haerlingen, Meghna Parakkal Shankar, Barbara De Faria Da Fonseca, Panos G. Ziros, Sumeet Pal Singh, Gerasimos Sykiotis, Sabine Costagliola. bioRxiv 2022.02.27.482168; doi: https://doi.org/10.1101/2022.02.27.482168
A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ cells to diabetes recovery in zebrafish
Sumeet Pal Singh, Prateek Chawla, Alisa Hnatiuk, Margrit Kamel, Luis F Delgadillo Silva, Bastiaan Spanjaard, Sema Elif Eski, Sharan Janjuha, Pedro Olivares Chauvet, Oezge Kayisoglu, Fabian Rost, Juliane Blasche, Annekathrin Krankel, Andreas Petzold, Thomas Kurth, Susanne Reinhardt, Jan Philipp Junker, Nikolay Ninov., Development (2022) 149 (2): dev199853. https://doi.org/10.1242/dev.199853
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, Bujko A, Martens L, Thoné T, Browaeys R, De Ponti FF, Vanneste B, Zwicker C, Svedberg FR, Vanhalewyn T, Gonçalves A, Lippens S, Devriendt B, Cox E, Ferrero G, Wittamer V , Willaert A, Kaptein SJF, Neyts J, Dallmeier K, Geldhof P, Casaert S, Deplancke B, Ten Dijke P, Hoorens A, Vanlander A, Berrevoet F, Van Nieuwenhove Y, Saeys Y, Saelens W, Van Vlierberghe H, Devisscher L, Scott CL. Cell. 2022 Jan 5:S0092-8674(21)01481-1. doi: 10.1016/j.cell.2021.12.018.
Repositioning For Allosteric Modulation of VIP and PACAP Receptors
Langer I, Latek D. Drug . Front Endocrinol (Lausanne). 2021 Nov 18;12:711906. doi: 10.3389/fendo.2021.711906. eCollection 2021.
Involvement of chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells
Estienne A, Mellouk N, Bongrani A, Plotton I, Langer I, Ramé C, Petit C, Guérif F, Froment P, Dupont J. Reproduction. 2021 Oct 28;162(6):427-436. doi: 10.1530/REP-21-0265.
Transcriptomic signature of human embryonic thyroid reveals transition from differentiation to functional maturation
Dom G., Dmitriev P., Lambot MA., Van Vliet G., Glinoer D., Libert F., Lefort A., Dumont J.E., Maenhaut C. (2021) . Frontiers in Cell and Developmental Biology 9,
MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways
Augenlicht A., Saiselet M., Decaussin-Petrucci M., Andry G., Dumont J.E., Maenhaut C. (2021) Oncotarget 12, 1587-1599.
Single-cell trajectory inference guided enhancement of thyroid maturation in vitro using TGF-beta inhibition
M. Romitti, S. E. Eski, B. F. Fonseca, P. Gillotay, S. P. Singh, and S. Costagliola, Front Endocrinol12, 657195 (2021).
Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia
Vercauteren Drubbel A, Pirard S, Kin S, Dassy B, Lefort A, Libert F, Nomura S, Beck B. Cell Stem Cell. 2021 Apr 14:S1934-5909(21)00152-1. doi: 10.1016/j.stem.2021.03.019. Epub ahead of print. PMID: 33882290.
In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration
M. I. Pronobis, S. Zheng, S. P. Singh, and K. D. Poss, bioRxiv, p. 2021.01.19.427246, Jan. 2021.
Novel inactivating follicle-stimulating hormone receptor mutations in a patient with premature ovarian insufficiency identified by next-generation sequencing gene panel analysis
A. Sassi, J. Désir, V. Janssens, M. Marangoni, D. Daneels, A. Gheldof, M. Bonduelle, S. Van Dooren, S. Costagliola, and A. Delbaere, F&S Reports, vol. 1, no. 3, pp. 193–201, Dec. 2020.
Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland
P. Gillotay, M. P. Shankar, S. E. Eski, S. Reinhardt, A. Kraenkel, J. Blaesche, A. Petzold, G. Kesavan, C. Lange, M. Brand, V. Detours, S. Costagliola, and S. P. Singh, EMBO Rep, vol. n/a, no. n/a, p. e50612, Nov. 2020.
Asymmetry in the frequency and position of mitosis in the mouse embryo epiblast at gastrulation
N. Mathiah, E. Despin-Guitard, M. Stower, W. Nahaboo, E. S. Eski, S. P. Singh, S. Srinivas, and I. Migeotte, EMBO Rep, vol. 9, no. n/a, p. 317, Oct. 2020.
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Q. Zhang et al. Science Sep. 2020, p. eabd4570. (Migeotte. I, IRIBHM)
Antibodies against carbamylated proteins: prevalence and associated disease characteristics in Belgian patients with rheumatoid arthritis or other rheumatic diseases.
Scandinavian journal of rheumatology, 1-6. https://doi:10.1080/03009742.2020.1798500. Sidiras, P., Spruyt, D., Gangji, V., Imbault, V., Sokolova, T., Durez, P., Communi, D., Rasschaert, J., & Badot, V. (2020).
Basement membrane remodelling regulates mouse embryogenesis
Kyprianou, C., Christodoulou, N., Hamilton, R. S., Nahaboo, W., Suárez-Boomgaard, D., Amadei, G., Migeotte, I., & Zernicka-Goetz, M. (2020) Nature (London), 582(7811), 253-258. doi:10.1038/s41586-020-2264-2
Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus
Delavallée, L., Mathiah, N., Cabon, L., Mazeraud, A., Brunelle-Navas, M.-N., Lerner,L. L., Tannoury, M., Prola, A., Moreno-Loshuertos, R., Baritaud, M., Vela, L., Garbin, K., Garnier, D., Lemaire, C., Langa-Vives,F., Cohen-Salmon, M., Fernández-Silva, P., Chretien, F., Migeotte, I., & Susin, S. A. (2020). M. Molecular metabolism, 40, 101027. doi:10.1016/ j.molmet.2020.101027
Effectiveness of benzyl benzoate treatment on clinical symptoms and Demodex density over time in patients with rosacea anddemodicosis:
a real life retrospective follow-up study comparing low- and high-dose regimens.
Forton FMN, De Maertelaer V. J Dermatolog Treat. 2020 Jun 15:1-10. doi:10.1080/09546634.2020.1770168. Epub ahead of print. PMID: 32427504.
Did Osteoblastic Cell Therapy Improve the Prognosis of Pre-fracture Osteonecrosis of the Femoral Head? A Randomized, Controlled Trial
Hauzeur JP, Lechanteur C, Baudoux E, De Maertelaer V, Pather S, Katz R,Malaise M, Ino J, Beguin Y.Clin Orthop Relat Res. 2020 Jun;478(6):1307-1315. doi:10.1097/CORR.0000000000001107. PMID: 31899739.