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Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit altered digestive homeostasis, Alia Hadefi, Morgane Leprovots, Gilles Dinsart, Maryam Marefati, Marjorie Vermeersch, Daniel Monteyne, David Perez Morga, Anne Lefort, Frederick Libert, Laurine Verset, Claire Liefferinckx, Christophe Moreno, Deviere Jacques, Eric Trepo, Marie-Isabelle Garcia, bioRxiv 2024.07.02.601648; doi: https://doi.org/10.1101/2024.07.02.601648.
Impact of benzo[a]pyrene, PCB153 and sex hormones on human ESC-Derived thyroid follicles using single cell transcriptomics, Marta Nazzari, Mírian Romitti, Anna M. Kip, Rick Kamps, Sabine Costagliola, Twan van de Beucken, Lorenzo Moroni, Florian Caiment, Environment International, 2024, https://doi.org/10.1016/j.envint.2024.108748.
Origin and flow-mediated remodeling of the murine and human extraembryonic circulation systems, Van Schoor Kristof , Bruet Emmanuel , Jones Elizabeth Anne Vincent , Migeotte Isabelle. Frontiers in Physiology, Volume 15 – 2024 |https://doi.org/10.3389/fphys.2024.1395006
STR mutations on chromosome 15q cause thyrotropin resistance by activating a primate-specific enhancer of MIR7-2/MIR1179, Grasberger H, Dumitrescu A M, Liao X-H, Swanson E G, Weiss R E, Srichomkwun P, Pappa T, Chen J, Yoshimura T, Hoffmann P, França M M, Tagett R, Onigata K, Costagliola S, Ranchalis J, Vollger M R, Stergachis A B, Chong J X, Bamshad M J, Smits G, Vassart G and Refetoff S, Nature Genetics (2024) https://doi.org/10.1038/s41588-024-01717-7
An Lgr5-independent developmental lineage is involved in mouse intestinal regenerationMarefati, M., Fernandez-Vallone, V., Leprovots, M., Vasile, G., Libert, F., Lefort, A., Dinsart, G., Weber, A., Jetzer, J., Garcia, M.-I., Vassart, G. bioRxiv Subject Collection: Developmental Biology / 2024-03-14 22:00
The olfactory receptor olfr78 promotes differentiation of enterochromaffin cells in the mouse colon, Gilles Dinsart, Morgane Leprovots, Anne Lefort, Frederick Libert, Yannick Quesnel, Alex Veiten, Gilbert Vassart, Sandra Huysseune, Marc Parmentier, Marie-Isabelle Garcia.
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Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids. H. Lasolle, A. Schiavo, A. Tourneur, P. Gillotay, B. de F. da Fonseca, L. Ceolin, O. Monestier, B. Aganahi, L. Chomette, M. M. L. Kizys, L. Haenebalcke, T. Pieters, S. Goossens, J. Haigh, V. Detours, A. L. S. Maia, S. Costagliola, and M. Romitti, Oncogene 1–16 (2023) doi:10.1038/s41388-023-02889-y.
Progress Toward and Challenges Remaining for Thyroid Tissue Regeneration, Mírian Romitti, Sabine Costagliola, Endocrinology, 2023;, bqad136, https://doi.org/10.1210/endocr/bqad136
A Systematic Review and Meta-analysis, Degeneffe A, De Maertelaer V, De Witte O, Lefranc F.The Association Between Meningioma and Breast Cancer: JAMA Netw Open. 2023 Jun 1;6(6):e2318620. doi: 10.1001/jamanetworkopen.2023.18620.
RHOJ controls EMT-associated resistance to chemotherapy ,Debaugnies M, Rodríguez-Acebes S, Blondeau J, Parent MA, Zocco M, Song Y, De Maertelaer V, Moers V, Latil M, Dubois C, Coulonval K, Impens F, Van Haver D, Dufour S, Uemura A, Sotiropoulou PA, Méndez J, Blanpain C.Nature. 2023 Apr;616(7955):168-175. doi: 10.1038/s41586-023-05838-7. Epub 2023 Mar 22.
The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes Simon Ullrich, Susanne Leidescher, Yana Feodorova, Katharina Thanisch, Jean-Baptiste Fini, Bernd Kaspers, Frank Weber, Boyka Markova, Dagmar Fuehrer, Mirian Romitti, Stefan Krebs, Helmut Blum, Heinrich Leonhardt, Sabine Costagliola, Heike Heuer, Irina Solovei
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Mesodermal FGF and BMP govern the sequential stages of zebrafish thyroid specification Benoit Haerlingen, Robert Opitz, Isabelle Vandernoot, Angelo Molinaro, Meghna Parakkal Shankar, Pierre Gillotay, Achim Trubiroha, Sabine Costagliola; Development 2023; dev.201023. doi: https://doi.org/10.1242/dev.201023
Modeling Braf-induced thyroid cancer development and drug screening using pluripotent stem cell-derived organoids H. Lasolle, A.A. Schiavo, A. Tourneur, P. Gilotay, B. de F. da Fonseca, L. Ceolin, O. Monestier, B. Aganahi, L. Chomette, M.K. Polisel, L. Haenabalcke, T. Pieters, S. Goossens, J. Haigh, V. Detours, A.L. Maia, S. Costagliola, M. Romitti, bioRxiv. (2023). https://doi.org/10.1101/2023.03.30.534915.
Single-cell transcriptomics uncovers the differentiation of a subset of murine esophageal progenitors into taste buds in vivo. Vercauteren Drubbel A, Beck B. Sci Adv. 2023 Mar 10;9(10):eadd9135. doi: 10.1126/sciadv.add9135. Epub 2023 Mar 8. PMID: 36888721; PMCID: PMC9995038.
Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody. Rovira M, Miserocchi M, Montanari A, Hammou L, Chomette L, Pozo J, Imbault V, Bisteau X, Wittamer V.Dev Dyn. 2023 Mar;252(3):400-414. https://doi.org/10.1002/dvdy.549
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“Emerging Technologies in Thyroid Biology: Pushing the Frontiers of Thyroid Research”, Costagliola, S., Singh, S. Molecular and Cellular Endocrinology, https://doi.org/10.1016/j.mce.2023.111912
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« Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis. » Michael Horckmans, Esteban Diaz Villamil, Céline Verdier, Henrik Laurell, H., Jean-Bernard Ruidavets, Lucas De Roeck, Guillaume Combes, Laurent O. Martinez and Didier Communi. Frontiers in Pharmacology (2022) https://doi.org/10.3389/fphar.2022.1049696
“Central role of PD-L1 in cardioprotection resulting from P2Y4 nucleotide receptor loss.” Michael Horckmans, Esteban Diaz Villamil, Mariaelvy Bianchini, Lucas De Roeck and Didier Communi. Frontiers in Immunology (2022). https://doi.org/10.3389/fimmu.2022.1006934
« UTP regulates the cardioprotective action of transplanted stem cells derived from mouse cardiac adipose tissue. » Esteban Diaz Villamil, Lucas De Roeck, Marion Vanorlé and Didier Communi. Frontiers in Pharmacology (2022) https://doi.org/10.3389/fphar.2022.906173
“Regionally specific levels and patterns of keratin 8 expression in the mouse embryo visceral endoderm emerge upon anterior-posterior axis determination”, Evangéline Despin-Guitard, Ronan Quenec’Hdu, Wallis Nahaboo, Nicole Schwarz, Rudolf E.Leube, Claire Chazaud and Isabelle Migeotte. Frontiers in Cell and Developmental Biology (2022) https://doi.org/10.3389/fcell.2022.1037041
“Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism” Mírian Romitti, Barbara de Faria da Fonseca, Gilles Doumont, Pierre Gillotay, Adrien Tourneur, Sema Elif Eski, Gaetan Van Simaeys, Laura Chomette, Helene Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, Samuel Refetoff, Sabine Costagliola Nat Commun 13, 7057 (2022). https://doi.org/10.1038/s41467-022-34776-7, https://doi.org/10.1038/s41467-022-34776-7
Loss of tetraspanin-7 expression reduces pancreatic beta-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism, Kerry McLaughlin, Samuel Acreman, Sameena Nawaz, Joseph Cutteridge, Anne Clark, Jakob G. Knudsen, Geoffrey Denwood, Aliya F. Spigelman, Jocelyn E. Manning Fox, Sumeet Pal Singh, Patrick E. MacDonald, Benoit Hastoy, Quan Zhang, Diabetic Medicine, 20 October 2022, https://doi.org/10.1111/dme.14984
“Murine Thyroid IL-4 Expression Worsens Hypothyroidism on Iodine Restriction and Mitigates Graves Disease Development.” Merakchi K, Djerbib S, Soleimani M, Dumont JE, Miot F, De Deken X. Endocrinology. 2022 Sep 1;163(9):bqac107. doi: 10.1210/endocr/bqac107.PMID: 35881515
“Cellular senescence modulates progenitor cell expansion during axolotl limb regeneration”, Qinghao Yu, Hannah E. Walters, Giovanni Pasquini, Sumeet Pal Singh, Daniel León-Periñán, Andreas Petzold, Preethi Kesavan, Cristina Subiran, Ines Garteizgogeascoa, Dunja Knapp, Anne Wagner, Andrea Bernardos, María Alfonso, Gayathri Nadar, Andreas Dahl, Volker Busskamp, Ramón Martínez-Máñez, Maximina H. Yun. bioRxiv, 2022.09.01.506196; https://doi.org/10.1101/2022.09.01.506196
“In vivo imaging of calcium dynamics in zebrafish hepatocytes”, Pozo-Morales, M., Garteizgogeascoa, I., Perazzolo, C., So, J., Shin, D. and Singh, S.P. (2022), . Hepatology. Accepted Author Manuscript. https://doi.org/10.1002/hep.32663
“Zebrafish Galectin 3 binding protein (Lgals3bp) is the target antigen of the microglial 4C4 monoclonal antibody”, Mireia Rovira, Alice Montanari, Latifa Hammou, Laura Chomette, Magali Miserocchi, Jennifer Pozo, Virginie Imbault, Xavier Bisteau, Valérie Wittamer
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“Foxe1 orchestrates thyroid and lung cell lineage divergence in mouse stem cell-derived organoids”, Fonseca B F, Barbee C, Romitti M, Eski S E, Gillotay P, Monteyne D, Perez-Morga D, Refetoff S, Singh S P and Costagliola S 2022 bioRxiv 2022.05.16.492074. https://doi.org/doi:10.1101/2022.05.16.492074.
« An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4 » Audrey G. Reeves, Angel Gonzalez-Valero, Patrick J. Moon, Edward Miller, Katia Coulonval, Steven W. M. Crossley, Xiao Xie, Dan He, Patricia Z. Musacchio, Alec H. Christian, Jeffrey M. McKenna, Richard A. Lewis, Eric Fang, Dustin Dovala, Yipin Lu, Lynn M. McGregor, Markus Schirle, John A. Tallarico, Pierre P. Roger, F. Dean Toste, and Christopher J. Chang. ChemRxiv (April 2022) https//doi.org/10.26434/chemrxiv-2022-9p94z
“Monoclonal antibodies to activated CDK4: Use to investigate normal and cancerous cell cycle regulation and involvement of phosphorylations of p21 and p27″ Coulonval, K., Vercruysse, V., Paternot, S., Pita, J.M., Corman, R., Raspé, E., Roger, P.P. Cell Cycle, 21(1) :12-32 (jan. 2022)
“Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of malignant pleural mesotheliomas to CDK4/6 inhibition “ Paternot S, Raspé E, Meiller C, Tarabichi M, Assié JB, Libert F, Remmelink M, Bisteau X, Pauwels P, Blum Y, Le Stang N, Tabone-Eglinger S, Galateau-Salle F, Blanquart C, Van Meerbeeck JP, Berghmans T, Jean D, Roger PP. bioRxiv (april 2022) doi: https://doi.org/10.1101/2022.04.11.487857
“The Atypical Chemerin Receptor GPR1 Displays Different Modes of Interaction with β-arrestins in Humans and Mice with Important Consequences on Subcellular Localization and Trafficking”. Degroot, G-N, Lepage, V., Parmentier M. and Springael, J-Y (2022) Cells in press.
“Signal Transduction by VIP and PACAP Receptors.” I. Langer, J. Jeandriens, A. Couvineau, S. Sanmukh, D. Latek. Biomedicines (2022) 9;10(2):406. doi: 10.3390/biomedicines10020406.
“Cold Atmospheric Plasma Differentially Affects Cell Renewal and Differentiation of Stem Cells and Apc-Deficient-Derived Tumor Cells in Intestinal Organoids.” A. Hadefi, M. Leprovots, M. Thulliez, O. Bastin, A. Lefort, F. Libert, A. Nonclercq, A. Delchambre, F. Reniers, J. Deviere, MI Garcia. Cell Death Discovery (2022) 8:66 ; https://doi.org/10.1038/s41420-022-00835-7.
“Keratin filaments mediate the expansion of extra-embryonic membranes in the post-gastrulation mouse embryo”, , , , , , , , , , , , , , , The EMBO Journal (2022) e108747.https://doi.org/10.15252/embj.2021108747
“Nrf2 promotes thyroid development and hormone synthesis”, Pierre Gillotay, Mirian Romitti, Benjamin Dassy, Benoit Haerlingen, Meghna Parakkal Shankar, Barbara De Faria Da Fonseca, Panos G. Ziros, Sumeet Pal Singh, Gerasimos Sykiotis, Sabine Costagliola. bioRxiv 2022.02.27.482168; doi: https://doi.org/10.1101/2022.02.27.482168
“A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ cells to diabetes recovery in zebrafish”, Sumeet Pal Singh, Prateek Chawla, Alisa Hnatiuk, Margrit Kamel, Luis F Delgadillo Silva, Bastiaan Spanjaard, Sema Elif Eski, Sharan Janjuha, Pedro Olivares Chauvet, Oezge Kayisoglu, Fabian Rost, Juliane Blasche, Annekathrin Krankel, Andreas Petzold, Thomas Kurth, Susanne Reinhardt, Jan Philipp Junker, Nikolay Ninov., Development (2022) 149 (2): dev199853. https://doi.org/10.1242/dev.199853
“Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches” Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, Bujko A, Martens L, Thoné T, Browaeys R, De Ponti FF, Vanneste B, Zwicker C, Svedberg FR, Vanhalewyn T, Gonçalves A, Lippens S, Devriendt B, Cox E, Ferrero G, Wittamer V , Willaert A, Kaptein SJF, Neyts J, Dallmeier K, Geldhof P, Casaert S, Deplancke B, Ten Dijke P, Hoorens A, Vanlander A, Berrevoet F, Van Nieuwenhove Y, Saeys Y, Saelens W, Van Vlierberghe H, Devisscher L, Scott CL. Cell. 2022 Jan 5:S0092-8674(21)01481-1. doi: 10.1016/j.cell.2021.12.018.
“In vivo imaging of calcium dynamics in zebrafish hepatocytes” Macarena Pozo-Morales, Ines Garteizgogeascoa, Camille Perazzolo, Sumeet Pal Singh, bioRxiv 2022.01.11.475536;
https://doi.org/10.1101/2022.01.11.475536
“Cold atmospheric plasma differentially affects cell renewal and differentiation of stem cells and APC-deficient-derived tumor cells in intestinal organoids”. Alia Hadefi, Morgane Leprovots, Max Thulliez, Orianne Bastin, Anne Lefort, Frederick Libert, Antoine Nonclercq, Alain Delchambre, Francois Reniers, Jacques Deviere, Marie-Isabelle Garcia. bioRxiv 2021.10.13.464287; doi: https://doi.org/10.1101/2021.10.13.464287
“Repositioning For Allosteric Modulation of VIP and PACAP Receptors”. Langer I, Latek D. Drug . Front Endocrinol (Lausanne). 2021 Nov 18;12:711906. doi: 10.3389/fendo.2021.711906. eCollection 2021.
“Involvement of chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells.” Estienne A, Mellouk N, Bongrani A, Plotton I, Langer I, Ramé C, Petit C, Guérif F, Froment P, Dupont J. Reproduction. 2021 Oct 28;162(6):427-436. doi: 10.1530/REP-21-0265.
“Transcriptomic signature of human embryonic thyroid reveals transition from differentiation to functional maturation”. Dom G., Dmitriev P., Lambot MA., Van Vliet G., Glinoer D., Libert F., Lefort A., Dumont J.E., Maenhaut C. (2021) . Frontiers in Cell and Developmental Biology 9,
“MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways”. Augenlicht A., Saiselet M., Decaussin-Petrucci M., Andry G., Dumont J.E., Maenhaut C. (2021) Oncotarget 12, 1587-1599.
“A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ cells to diabetes recovery in zebrafish”, Sumeet Pal Singh, Prateek Chawla, Alisa Hnatiuk, Margrit Kamel, Luis F Delgadillo Silva, Bastiaan Spanjaard, Sema Elif Eski, Sharan Janjuha, Pedro Olivares Chauvet, Oezge Kayisoglu, Fabian Rost, Juliane Blasche, Annekathrin Krankel, Andreas Petzold, Thomas Kurth, Susanne Reinhardt, Jan Philipp Junker, Nikolay Ninov. bioRxiv 2021.06.24.449704; doi: https://doi.org/10.1101/2021.06.24.449704
“Single-cell trajectory inference guided enhancement of thyroid maturation in vitro using TGF-beta inhibition,” M. Romitti, S. E. Eski, B. F. Fonseca, P. Gillotay, S. P. Singh, and S. Costagliola, Front Endocrinol12, 657195 (2021).
“Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia”. Vercauteren Drubbel A, Pirard S, Kin S, Dassy B, Lefort A, Libert F, Nomura S, Beck B. Cell Stem Cell. 2021 Apr 14:S1934-5909(21)00152-1. doi: 10.1016/j.stem.2021.03.019. Epub ahead of print. PMID: 33882290.
“In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration,” M. I. Pronobis, S. Zheng, S. P. Singh, and K. D. Poss, bioRxiv, p. 2021.01.19.427246, Jan. 2021.
“Novel inactivating follicle-stimulating hormone receptor mutations in a patient with premature ovarian insufficiency identified by next-generation sequencing gene panel analysis,” A. Sassi, J. Désir, V. Janssens, M. Marangoni, D. Daneels, A. Gheldof, M. Bonduelle, S. Van Dooren, S. Costagliola, and A. Delbaere, F&S Reports, vol. 1, no. 3, pp. 193–201, Dec. 2020.
“Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland,” P. Gillotay, M. P. Shankar, S. E. Eski, S. Reinhardt, A. Kraenkel, J. Blaesche, A. Petzold, G. Kesavan, C. Lange, M. Brand, V. Detours, S. Costagliola, and S. P. Singh, EMBO Rep, vol. n/a, no. n/a, p. e50612, Nov. 2020.
“Asymmetry in the frequency and position of mitosis in the mouse embryo epiblast at gastrulation”, N. Mathiah, E. Despin-Guitard, M. Stower, W. Nahaboo, E. S. Eski, S. P. Singh, S. Srinivas, and I. Migeotte, EMBO Rep, vol. 9, no. n/a, p. 317, Oct. 2020.
“Inborn errors of type I IFN immunity in patients with life-threatening COVID-19,” Q. Zhang et al. Science Sep. 2020, p. eabd4570. (Migeotte. I, IRIBHM)
“Basement membrane remodelling regulates mouse embryogenesis”. Kyprianou, C., Christodoulou, N., Hamilton, R. S., Nahaboo, W., Suárez-Boomgaard, D., Amadei, G., Migeotte, I., & Zernicka-Goetz, M. (2020) Nature (London), 582(7811), 253-258. doi:10.1038/s41586-020-2264-2
“Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus” Delavallée, L., Mathiah, N., Cabon, L., Mazeraud, A., Brunelle-Navas, M.-N., Lerner,L. L., Tannoury, M., Prola, A., Moreno-Loshuertos, R., Baritaud, M., Vela, L., Garbin, K., Garnier, D., Lemaire, C., Langa-Vives,F., Cohen-Salmon, M., Fernández-Silva, P., Chretien, F., Migeotte, I., & Susin, S. A. (2020). M. Molecular metabolism, 40, 101027. doi:10.1016/ j.molmet.2020.101027
“Effectiveness of benzyl benzoate treatment onclinical symptoms and Demodex density over time in patients with rosacea anddemodicosis: a real life retrospective follow-up study comparing low- and high-dose regimens”. Forton FMN, De Maertelaer V. J Dermatolog Treat. 2020 Jun 15:1-10. doi:10.1080/09546634.2020.1770168. Epub ahead of print. PMID: 32427504.
“Did Osteoblastic Cell Therapy Improve the Prognosis of Pre-fracture Osteonecrosis of the Femoral Head? A Randomized, Controlled Trial”. Hauzeur JP, Lechanteur C, Baudoux E, De Maertelaer V, Pather S, Katz R,Malaise M, Ino J, Beguin Y.Clin Orthop Relat Res. 2020 Jun;478(6):1307-1315. doi:10.1097/CORR.0000000000001107. PMID: 31899739.
“Digenic inheritance of human primarymicrocephaly delineates centrosomal and non-centrosomal pathways”. Duerinckx S, Jacquemin V, Drunat S, Vial Y, Passemard S, Perazzolo C, MassartA, Soblet J, Racapé J, Desmyter L, Badoer C, Papadimitriou S, Le Borgne YA,Lefort A, Libert F, De Maertelaer V, Rooman M, Costagliola S, Verloes A,Lenaerts T, Pirson I, Abramowicz M. Hum Mutat.2020 Feb;41(2):512-524. doi: 10.1002/humu.23948. Epub 2019 Nov 27. PMID:31696992.
“LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling ” Alessandra Mancini, Sasha R. Howard, Federica Marelli, Claudia P. Cabrera, Michael R. Barnes, Michael J.E. Sternberg, Morgane Leprovots, Irene Hadjidemetriou, Elena Monti, Alessia David, Karoliina Wehkalampi, Roberto Oleari, Antonella Lettieri, Valeria Vezzoli, Gilbert Vassart, Anna Cariboni, Marco Bonomi, Marie Isabelle Garcia, Leonardo Guasti, and Leo Dunkel. CI Insight. 2020;5(11):e133434
“LGR5 controls extracellular matrix production by stem cells in the developing intestine,” V. Fernandez Vallone, M. Leprovots, D. Ribatallada-Soriano, R. Gerbier, A. Lefort, F. Libert, G. Vassart, and M.-I. Garcia, EMBO Rep, vol. 3, no. n/a, p. 038, May 2020.
“APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.” Uzureau S, Lecordier L, Uzureau P, Hennig D, Graversen JH, Homblé F, Mfutu PE, Oliveira Arcolino F, Ramos AR, La Rovere RM, Luyten T, Vermeersch M, Tebabi P, Dieu M, Cuypers B, Deborggraeve S, Rabant M, Legendre C, Moestrup SK, Levtchenko E, Bultynck G, Erneux C, Pérez-Morga D, Pays E. Cell Rep. 2020 Mar 17;30(11):3821-3836
“Yolk sac hematopoiesis: does it contribute to the adult hematopoietic system?” Wittamer V, Bertrand JY. Cell Mol Life Sci. 2020 May 13. doi: 10.1007/s00018-020-03527-6.
“Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes.”Kuil LE, Oosterhof N, Ferrero G, Mikulášová T, Hason M, Dekker J, Rovira M, van der Linde HC, van Strien PM, de Pater E, Schaaf G, Bindels EM, Wittamer V, van Ham TJ. Elife. 2020 May 5;9. pii: e53403. doi: 10.7554/eLife.53403.
“Macrophage-expressed gene (mpeg)1 identifies a subpopulation of B cells in the adult zebrafish””.Giuliano Ferrero, Etienne Gomez, Sowmya lyer, Mireia Rovira, Magali Miserocchi, David M. Langenau, Julien Y. Bertrand and Valérie Wittamer. (2020) Journal of Leukocyte Biology. Mar;107(3):431-443. doi: 10.1002/JLB.1A1119-223R.
“An asymmetry in the frequency and position of mitosis in the epiblast precedes gastrulation and suggests a role for mitotic rounding in cell delamination during primitive streak epithelial-mesenchymal transition”, Navrita Mathiah*, Evangéline Despin-Guitard*, Matthew Stower, Wallis Nahaboo, Elif Sema Eski, Sumeet Pal Singh, Shankar Srinivas, Isabelle Migeotte, Biorxiv doi: https://doi.org/10.1101/2020.02.21.959080
“Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing”, Mcheik S, Van Eeckhout N, De Poorter C, Galés C, Parmentier M, Springael JY. Front Immunol. 2019 Dec 18;10:2970. doi: 10.3389/fimmu.2019.02970. eCollection 2019. PMID: 31921208
“Reprogramming of energy metabolism: increased expression and roles of pyruvate carboxylase in papillary thyroid cancer”. Strickaert A., Corbet C., Spinette S., Craciun L., Dom G., Andry G., Larsimont D., Wattiez R., Dumont J.E., Feron O., Maenhaut C. (2019) . Thyroid 29; 845-857
“Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects,” I.Vandernoot, B. Haerlingen, A. Trubiroha, P. Gillotay, V. Janssens, R. Opitz, and S. Costagliola, bioRxiv, p. 2019.12.19.880815, Dec. 2019.
“Phosphoinositide 5-phosphatases SKIP and SHIP2 in ruffles, the endoplasmic reticulum and the nucleus: an update”. Ana Raquel Ramos, Somadri Ghosh, Tara Suhel, Clément Chevalier, Eric Owusu Obeng, Bohumil Fafílek, Pavel Krejci, Benjamin Beck, Christophe Erneux (2019) Adv Biol Regulation. in press.
“Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis”, Ingrid Dubois-Vedrenne, Olivier De Henau, Virginie Robert, Francina Langa, Diana Al Delbany, Olivier Vosters, Edgar Angelats-Canals, Maxime Vernimmen, Souphalone Luangsay, Valérie Wittamer, and Marc Parmentier, (2019) Frontiers in Oncology, In press
“Inhibition of the thyroid hormonogenic H2O2 production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound”, Nicoletta Giusti, Pierre Gillotay, Achim Trubiroha, Robert Opitz, Jacques-Emile Dumont, Sabine Costagliola, Xavier De Deken, Molecular and Cellular Endocrinology, 2019, 110635, ISSN 0303-7207, https://doi.org/10.1016/j.mce.2019.110635.
“Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development”. Benoit Haerlingen, Robert Opitz, Isabelle Vandernoot, Achim Trubiroha, Pierre Gillotay, Nicoletta Giusti, Sabine Costagliola. 2019, Sept 11, Thyroid; https://doi.org/10.1101/55186
“Lgr5 controls extracellular matrix production by stem cells in the developing intestine.”Fernandez-Vallone V., Leprovots M., Gerbier R., Ribatallada-Soriano D., Lefort A., Libert F., Vassart G., Garcia MI. BIORXIV/2019/757641.
“Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways,” Bonnefont, L. Tiberi, J. van den Ameele, D. Potier, Z. B. Gaber, X. Lin, A. Bilheu, A. Herpoel, F. D. Velez Bravo, F. Guillemot, S. Aerts, and P. Vanderhaeghen, Neuron, Jul. 2019.
“Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo”. B. Saykali, N. Mathiah, W. Nahaboo, M.-L. Racu, L. Hammou, M. Defrance, and I. Migeotte, eLife, vol. 8, p. e42434, 2019.
“Lipid phosphatases SKIP and SHIP2 regulate fibronectin-dependent cell migration in glioblastoma”. Ramos AR, Ghosh S, Dedobbeleer M, Robe PA, Rogister B, Erneux C.FEBS J. 2019 Jan 29. doi: 10.1111/febs.14769.
“The impact of PI 5-phosphatases on phosphoinositides in cell function and human disease” Ana Raquel Ramos, Somadri Ghosh, Christophe Erneux (2019) J. Lipid Res. 60: 2. 276-286 Feb.
“Inhibition of SHIP2 activity inhibits cell migration and could prevent metastasis in breast cancer cells”,Somadri Ghosh, Samuel Scozzaro, Ana Raquel Ramos, Sebastien Delcambre, Clement Chevalier, Pavel Krejci, and Christophe Erneux. 2018 Journal of Cell science, Aug 16;131(16), pii: jcs216408.
“Embryonic microglia derive from primitive macrophages and are replaced by cmyb-dependent definitive microglia in zebrafish”, Giuliano Ferrero, Christopher B. Mahony, Eléonore Dupuis, Laurent Yvernogeau, Elodie Di Ruggiero, Magali Miserocchi, Marianne Caron, Catherine Robin, David Traver, Julien Y. Bertrand and Valérie Wittamer. Cell Rep. 2018 Jul 3;24(1):130-141
“Human-specific NOTCH2NL genes expand cortical neurogenesis through Delta/Notch regulation,” Suzuki IK, Gacquer D, Van Heurck R, Kumar D, Wojno M, Bilheu A, Herpoel A, Cheron J, Polleux F, Detours V, and Vanderhaeghen P. Cell, Volume 173, Issue 6, 31 May 2018, Pages 1370–1384.e16
“Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way”,Ira Espuny-Camacho, Kimmo A. Michelsen, Daniele Linaro, Angéline Bilheu, Sandra Acosta-Verdugo, Adèle Herpoel, Michele Giugliano, Afsaneh Gaillard, Pierre Vanderhaeghen, Cell Reports, Volume 23, Issue 9, 29 May 2018, Pages 2732-2743.
“A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function,” A. Trubiroha, P. Gillotay, N. Giusti, D. Gacquer, F. Libert, A. Lefort, B. Haerlingen, X. Deken, R. Opitz, and S. Costagliola, Sci. Rep., pp. 1–19, Mar. 2018.
“Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Receptor Function.” Peyrassol X, Laeremans T, Lahura V, Debulpaep M, El Hassan H, Steyaert J, Parmentier M, Langer I. Front Endocrinol (Lausanne). 2018 Apr 5;9:153.