Open Positions

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   Recent Publications

“Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development”. Benoit Haerlingen, Robert Opitz, Isabelle Vandernoot, Achim Trubiroha, Pierre Gillotay, Nicoletta Giusti, Sabine Costagliola. 2019, Sept 11, Thyroid; https://doi.org/10.1101/55186

"Lgr5 controls extracellular matrix production by stem cells in the developing intestine."Fernandez-Vallone V., Leprovots M., Gerbier R., Ribatallada-Soriano D., Lefort A., Libert F., Vassart G., Garcia MI. BIORXIV/2019/757641.

“Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways,” Bonnefont, L. Tiberi, J. van den Ameele, D. Potier, Z. B. Gaber, X. Lin, A. Bilheu, A. Herpoel, F. D. Velez Bravo, F. Guillemot, S. Aerts, and P. Vanderhaeghen, Neuron, Jul. 2019.

“Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo”. B. Saykali, N. Mathiah, W. Nahaboo, M.-L. Racu, L. Hammou, M. Defrance, and I. Migeotte, eLife, vol. 8, p. e42434, 2019.

"Lipid phosphatases SKIP and SHIP2 regulate fibronectin-dependent cell migration in glioblastoma". Ramos AR, Ghosh S, Dedobbeleer M, Robe PA, Rogister B, Erneux C.FEBS J. 2019 Jan 29. doi: 10.1111/febs.14769.

"The impact of PI 5-phosphatases on phosphoinositides in cell function and human disease" Ana Raquel Ramos, Somadri Ghosh, Christophe Erneux (2019)  J. Lipid Res. 60:  2.  276-286 Feb. 

   Seminars

September 2019
Biomedical Research Seminars
Campus Erasme - 1PM

September 12 (Auditoire Louise Popelin. Bt W)
Nicolas Rivron
Laboratory of Synthetic Development-IMBA-Austrian Academy of Sciences, Vienna, Austria
“Synthetic development: self organization of stem cells into embryo models"
Host: S. Costagliola

September 19 (Auditoire Louise Popelin. Bt W)
Tom Vanden Berghe
Department of Biomedical Sciences - Laboratory of Pathophysiology- University of Antwerp
"Ferroptosis and inflammation research in critical illness"
Host: A K. Cardozo

September 26 (Auditoire Louise Popelin. Bt W)
Mikael Nilsson
Sahlgrenska Cancer center - Institute of Biomedicine - University of Gothenburg
"Stochastic activation of mutant Braf modeling sporadic thyroid cancer development"
Host: C. Maenhaut

   Press release

New European H2020 research project
The influence of endocrine disruptors on the male and female thyroid gland

The new European collaborative project SCREENED aims to develop three-dimensional (3D) cell-based in vitro tests to better characterize the effects of endocrine disruptors on thyroid functions. This method will overcome the limitations of existing tests, being more sensitive, at low doses of exposure to chemicals, and enabling the prediction of their toxicity on human health in a sex-specific manner. Sabine Costagliola Lab at IRIBHM is the Belgian partner of this ambitious and innovative project.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 825745.

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