Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis

P2Y receptorsArtery diseaseCardiac
Written By Aleks

Michael Horckmans, Esteban Diaz Villamil, Céline Verdier, Henrik Laurell, H., Jean-Bernard Ruidavets, Lucas De Roeck, Guillaume Combes, Laurent O. Martinez and Didier Communi. Frontiers in Pharmacology (2022) https://doi.org/10.3389/fphar.2022.1049696

Aleks
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Central role of PD-L1 in cardioprotection resulting from P2Y4 nucleotide receptor loss