PhD Day June 2022


After a two-year break, IRIBHM is pleased to announce the 7th PhD Day on June 17, 2022 at Holleken Farm.

The goal of this day is to propose an overview of the scientific work within the Institute, but also to reactivate the social networking that has been severely affected by the two-year health crisis.
As in previous years, external groups with which IRIBHM has close relationships will participate in this day, in particular the Neurophysiology Laboratory of the Faculty of Medicine and the Neurovascular Signaling Laboratory of the Faculty of Science.
The scientific program will be divided into oral presentations and flash talks/poster sessions, at the end of which the best speaker in each exercise will be awarded.
This day will conclude with a BBQ and a few beers.
As with the previous editions, we would like to organize an eco-friendly day with zero non-recyclable waste. To achieve this, we count on everyone’s participation and ask all talented cooks and pastry chefs to bring savory or sweet preparations that will enrich our coffee breaks.

See you on June 17 to reconnect together again



June 17, 2022, 7th IRIBHM PhD Day

09:00 – 09:30

Arrivals & Welcome introduction

09:30 – 10:15

Session 1: – Soon You’ll Get Better (Taylor Swift) (talks 15min + 5 for questions)

Chair: Meghna Parakkal Shankar (S. Costagliola)

  • Cindy Van Branteghem (C. Maenhaut) Functional roles of miR-204-5p and HMGA2 in thyroid tumorigenesis”.
  • Esteban Diaz Villamil (Di. Communi)UTP regulates the cardioprotective action of transplanted stem cells derived from mouse cardiac adipose tissue”.

10:15- 10:30

Flash talks (5 Flash talks 3 min.) Odd Numbers 1 to 9: 

1- Romain Darche (I. Pirson-M. Parmentier) Functional study of an orphan GPCR subfamily using zebrafish genetic models”.
3- Jérôme Jeandriens (I. Langer)The VIP-VPAC1 pathway among the heterogeneity of human colon fibroblasts”
5- Junior Badziak (P. Laurent) “The germline-expressed retrotransposon cer1 promotes cold tolerance in C. elegans”.
7- Zhang Zhao (V. Detours) The Canguilhem study: Unbiased quantitative survey of human asymptomatic thyroid morphologies and associated transcriptional and genetics variations”.
9- Fabiana Moresi (B.Beck- X.Bisteau) “The dynamic response of esophageal cancer to CDK4/6 inhibition triggers chromosome instability via the rewiring of its proteome”.

10:30- 11:00            Coffee break

11:00 – 11:45

Session 2: A Kind of Magic (Queen) (talks 15min + 5 for questions)

Chair: Adrien Tourneur (V. Detours)

  • Frank Maurinot (Vanderhaeghen)Exploring a realization of the human cerebral cortex: genetic screening in an organoid model”.
  • Mirian Romitti (Costagliola)Generation of a bipotent human pluripotent stem cell-derived organoid model: How to make thyroid or lung from NKX2-1-expressing cells?”

11:45- 12:00

Flash talks 5 Flash talks 3 min) Odd Numbers 11 to 19:

11Giel Schevenels (B. Vanhollebeke) “Organotypic angiogenic programs: insights from CNS endothelial tip cells”.
13Sandra Fauli Perpina (A. De Kerchove) “Unraveling the contributions of the direct and indirect striatal projection neurons to cognitive flexibility in a fixed-ratio 1-5 operant task”.
15Edwige Martin-valiente (N. Baeyens)Contribution of mechanical forces from blood flow in neurovascular aneurysmal malformations”.
17- Pauline de Meyer (V. Wittamer) New insights into the cellular and molecular mechanisms regulating microglia cell fate in vivo”.
19- Sema Elif Eski (S. Pal Singh) “A Triangular Theme: the function of ATP-Citrate Lyase (ACLY) in cellular stress, lipogenesis and epigenetic regulation in zebrafish liver upon ethanol exposure”.

12:00 – 13:00           Lunch

13:00 – 14:00  Posters session

14:00 – 14:45

Session 3: – Private Investigations  (Coldplay)  (talks 15min + 5 for questions)

Chair: Mehmet Can Demirler (V. Wittamer)

  • Karima Meracki (X. De Deken- F. Miot) “Differential impact of intrathyroidal IL-4 expression on thyroiditis development in C57BL/6j and H2h4Thyr-IL4 mice”.
  • Christophe Varin (A. De Kerchove)Asymmetric encoding dynamics in the striatal direct and indirect pathways during spontaneous behaviour”.
  • Gilles Dinsart (I. Garcia) “Investigation of the physiological role of the ectopically expressed mouse olfactory receptors Olfr78 and Olfr558 receptors in the intestinal tract”.

15:00- 15:15   

Flash talks (5 Flash talks 3 min): Even Numbers 2 to 10

2- Michelle America (B. Vanhollebeke) “An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates”.
4- Alice Montanari (V. Wittamer) “Microglia-endothelial cell crosstalk during brain development”.
6- Valerie Vandenbempt (E. Gurzov) “Single-cell sequencing reveals preserved pancreatic islet-cell identity by administration of metabolite-based diet in autoimmune diabetes”.
8- Macarena Pozo Morales (S. Pal Singh) “Mobilization of endo lysosomal calcium stores reduces lipids in the liver”.
10- Teresa Lobo (P. Laurent) “Biogenesis of extracellular vesicles in C. elegans”.

15:00 – 15:30           Coffee break

15:30 – 16:15

Session 4: Under Control (The Strokes) (talks 15min + 5 for questions)

Chair: Ana Raquel Ramos (B. Beck)

  • Catarina Stratigi (P. Laurent) “PPRP-1/PHACTR1 holophosphatase controls synaptic vesicle cycle in C. elegans”.
  • Benjamin Dassy (B.Beck) “Microenvironment fine tunes plasticity of esophageal keratinocytes”.

16:30 – 16:45

Flash talks (Flash talks 3 min) Even Numbers 12 to 18:

12- Wadsen Saint-Pierre Wijckmans (E. Gurzov) “Receptor type protein tyrosine phosphatase F (PTPRF) as potential therapeutic target for hepatic steatosis and HCC development in obesity”.
14- Mariam Marefati (I. Garcia) “Intestinal regeneration: contribution to the identification of the cell lineages involved”.
16- Jennifer Pozo Gomez (V. Wittamer) “Utilizing zebrafish for new insights into the roles of chemerin in cancer biology”.
18- Sami Djerbib (X. De Deken – F. Miot) “Study of the role of hydrogen peroxide in thyroid tumorigenesis in a new transgenic mouse model overexpressing the DUOX/DUOXA H₂O₂ generating system”.

16:45-17:45   Posters session

17:45   Conclusion and prizes

Social hour (beer session, appetizers, entertainment)

19:00-22:00         BBQ party

*Poster format: Vertical 90 cm L X 120 cm H (A0)


Ferme De Holleken

Directions :

BUS : De Lijn 155 (19mn from CERIA)

TRAIN : Line 124 Bruxelles-Charleroi (Holleken train station)

CAR: Follow this link