Gilbert VASSART group


LGRs receptors as peculiar GPCRs involved in cancer (Review). Garcia MI.
J Stem Cell Res Med 2017, doi: 10.15761/JSCRM.1000116.


Ex vivo culture of gastric spheroids. Fernandez Vallone V., Leprovots M., Vassart G and Garcia MI.
Bio-protocols . 2017. DOI 10.21769/2089.


Ex vivo culture of adult antral glands. Fernandez Vallone V., Leprovots M., Vassart G and Garcia MI.
Bio-protocols. 2017. DOI 10.21769/2088.


LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea. Zak, Magdalena; Van Oort, Thys; Hendriksen, Ferry G; Garcia, Marie-Isabelle; Vassart, Gilbert; Grolman, Wilko
Front Cell Neurosci. 2016; 10: 186. doi:  10.3389/fncel.2016.00186     PMCID: PMC4988241


Stem Cells in Adult Homeostasis, Regeneration and Tissue Development of the Digestive Tract Epithelium. Valeria Fernandez Vallone and Marie-Isabelle Garcia
Int J Stem Cell Res Ther 2016, 3:038 Volume 3 | Issue 2 ISSN: 2469-570X


Building and rebuilding gastric epithelium: Trop2 as a common denominator. Valeria Fernandez Vallone and Marie-Isabelle Garcia.
Atlas of Science, another view on science.
Published online August 15th, 2016.


Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage: Fernandez Vallone V, Leprovots M, Strollo S, Vasile G, Lefort A, Libert F, Vassart G, Garcia MI.

Development. 2016 May 1;143(9):1452-63. doi: 10.1242/dev.131490. Epub 2016 Mar 17.


Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium: Mustata RC, Vasile G, Fernandez-Vallone V, Strollo S, Lefort A, Libert F, Monteyne D, Pérez-Morga D, Vassart G, Garcia MI. Cell Rep. 2013 Oct 31;5(2):421-32.

Identification des progéniteurs de l’épithélium intestinal foetal: M/S médecine/sciences. 2014 4:353-355. Garcia MI, Vassart G.

Chapter entitled :”Discovery and Characterization of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors from the book “The Genetics of G Protein-Coupled Receptors: Methods for the Post-Genomic Era” edited by Craig W. Stevens, PhD; Springer Science+Business Media, LLC; Humana Press. MI Garcia, V. Fernandez-Vallone and G. Vassart.

Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo. Mustata RC, Van Loy T, Lefort A, Libert F, Strollo S, Vassart G, Garcia MI. EMBO Rep. 2011 Jun;12(6):558-64.

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G. Dev Biol. 2009 Jul 1;331(1):58-67.

Three-dimensional reconstruction of efferent ducts in wild-type and Lgr4 knock-out mice. Lambot MA, Mendive F, Laurent P, Van Schoore G, Noël JC, Vanderhaeghen P, Vassart G. Anat Rec (Hoboken). 2009 Apr;292(4):595-603.

Defective postnatal development of the male reproductive tract in LGR4 knockout mice. Mendive F, Laurent P, Van Schoore G, Skarnes W, Pochet R, Vassart G. Dev Biol. 2006 Feb 15;290(2):421-34.

Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse. Van Schoore G, Mendive F, Pochet R, Vassart G. Histochem Cell Biol. 2005 Jul;124(1):35-50.

Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2. Mendive FM, Van Loy T, Claeysen S, Poels J, Williamson M, Hauser F, Grimmelikhuijzen CJ, Vassart G, Vanden Broeck J. FEBS Lett.2005 Apr 11;579(10):2171-6

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